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Gamma Knife Radiosurgery
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OPHTHALMOLOGY

Treatment of Choroidal or Uveal Melanomas with Gamma Knife Surgery

Choroidal melanomas are the second most common intraocular malignancy after metastases. The annual incidence is approximately 7 per 1 million, and the mortality rate is approximately 50% at 10 years. Historically these tumors have been managed by enucleation (removal of the eye globe) while the current management is directed towards preserving the eye when possible. Treatment options include observation, cryotherapy, photocoagulation, plaque brachy therapy, proton beam radiotherapy and most recently the introduction of gamma knife surgery (GKS). The advantages of GKS include the minimally invasive nature of the surgery, with no need for general anesthesia, hospitalization, or open surgery. The control rates with GKS have been reported to be over 85%.


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