Regional Immunization Manual
Competency #4: The Types of Immunizing Agents and their Composition
Competency: Applies the knowledge of the components and properties of immunizing agents as needed for safe and effective practice.
The health professional will be able to perform the following:
- Classify each immunizing agent used in practice as live attenuated, inactivated, or subunit.
- Demonstrate the ability to describe live attenuated, inactivated, and subunit immunizing agents to an audience with minimal or no science knowledge.
- Compare the major advantages and disadvantages of live attenuated versus inactivated/subunit immunizing agents.
- Identify key differences in the immune response to purified polysaccharide versus polysaccharide protein conjugate vaccines.
- Describe, in general terms, the purpose, action and potential concerns of each of the following components that may be present in a given vaccine product: adjuvant, preservative, additives, glass vial, stopper, and prefilled syringe.
- Locate and utilize current information resources on the types and content of immunizing agents used in practice.
- Immunizing Agents- Current information on the various vaccines can be found in the Canadian Immunization Guide.
Vaccine Fact Sheets - Current vaccine fact sheets and information on vaccine preventable diseases can be found on the Manitoba Health Website.
What’s in a vaccine? - Canadian Immunization Guide
Types of Vaccine and Their Content - Canadian Immunization Guide
Vaccine Preventable Disease Information - Manitoba Health Communicable Disease Management Protocols and Fact Sheets
Addressing parents' concerns: do vaccines contain harmful preservatives, adjuvants, additives, or residuals?Offit, P.A., & Jew, R.K. (2003) Pediatrics, Vol 112, No.6., pages 1394 - 1401.
Principles of Vaccination - Centers for Disease Control and Prevention (2009). Epidemiology and Prevention of Vaccine-Preventable Diseases (11th ed.) - Chapter 1
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